A first period is devoted to prototyping. Our biological goals are to improve the percentage of recombinant proteins in our strains (% TSP), adapt them to heterotrophic growth (on a carbon source without light), develop our vectoring tools and demonstrate the concept of our targets with in-vitro validation.
We focus on two therapeutic areas: oncology and infectiology, with recombinant immunotoxins ('RITs'), called "hostile" proteins because of the difficulty of producing these toxic compounds in conventional cellular systems (which is much easier in plant cells), with anti-microbial and anti-viral peptides, with antigenic peptide vaccines.
For oral, mucosal or topical medications, our Research and Innovation program will move the vectoring of active ingredients in the microalgal cell from the concepts to an industrial stage, relying on academic and private partners.
1- USP production preferentially in fermenters, extremely productive qualified tools, or in combination with photobioreactors depending on the microalgae strain, collaborating with OEMs to adapt their best tools to our pharmaceutical quality requirements.
2- a DSP treatment that allows effective vectoring of our targets, with attention to "active delivery" and "controlled release".
We will be producing biotherapeutics samples as early as the 3rd year in our ISO-certified lab that respects Good Laboratory Practices. The entire process will increase production from a few milligrams to ten grams (screening and feasibility samples, then batches for toxicological and pharmacological studies).